Article
FADD-calmodulin interaction: a novel player in cell cycle regulation.
Biochimica et biophysica acta - 1 Aug 2010
Papoff Giuliana, Trivieri Nadia, Crielesi Roberta, Ruberti Francesca, Marsilio Sonia, Ruberti Giovina
Abstract excerpt
Analyses of knockout and mutant transgenic mice as well as in vitro studies demonstrated a complex role of FADD in the regulation of cell fate. FADD is involved in death receptor induced apoptosis, cell cycle progression and cell proliferation. In a search for mechanisms that might regulate FADD functions, we identified, upon the screening of a lambda-phage cDNA library, calmodulin (CaM) as a novel FADD...
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