N-terminal and C-terminal domains of calmodulin mediate FADD and TRADD interaction.

doi:10.1371/journal.pone.0116251

Article

N-terminal and C-terminal domains of calmodulin mediate FADD and TRADD interaction.

PloS one - 1 Jan 2015

Papoff Giuliana, Trivieri Nadia, Marsilio Sonia, Crielesi Roberta, Lalli Cristiana, Castellani Loriana, Balog Edward M, Ruberti Giovina

Abstract excerpt

FADD (Fas-associated death domain) and TRADD (Tumor Necrosis Factor Receptor 1-associated death domain) proteins are important regulators of cell fate in mammalian cells. They are both involved in death receptors mediated signaling pathways and have been linked to the Toll-like receptor family and innate immunity. Here we identify and characterize by database search analysis, mutagenesis and calmodulin (CaM)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

N-terminal and C-terminal domains of calmodulin mediate FADD and TRADD interaction.

Abstract excerpt

Topics

N-terminal and C-terminal domains of calmodulin mediate FADD and TRADD interaction.

Abstract excerpt

Topics

Related research