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Article

A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicularfeminized mouse

1 Jan 1991

Abstract excerpt

The testicular feminized (Tfm) mouse lacks completely androgen responsiveness; and therefore, is unique for studying the role of androgenic steroids in different biological processes. In order to understand the molecular basis of this mutation, 2.8 kilobases of cDNA encoding the Tfm mouse androgen receptor (AR) were amplified with a polymerase chain reaction (PCR) technique. No large deletion in the coding region...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Identifiers

PMID: 2041777
DOI: 10.1093/nar/19.9.2373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicularfeminized mousePMID 2041777Read ↗

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