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A Frameshift Mutation Destabilizes Androgen Receptor Messenger RNA in the<i>Tfm</i>Mouse

1 Apr 1991

Abstract excerpt

A composite mouse androgen receptor DNA sequence was obtained by amplifying genomic DNA or cDNA using the polymerase chain reaction. The open reading frame was 2,697 basepairs, encoding a polypeptide of 899 amino acids (98,204 mol wt). Amino acid sequence comparisons indicated that the mouse androgen receptor (AR) is 97% homologous with rat AR and 83% with human AR. The amino acid sequences of the three receptors...

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PMID: 1681426
DOI: 10.1210/mend-5-4-573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A Frameshift Mutation Destabilizes Androgen Receptor Messenger RNA in the<i>Tfm</i>MousePMID 1681426Read ↗

A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicularfeminized mouseSemantic proximity Read ↗

A single base deletion in the Tfm androgen receptor gene creates a short-lived messenger RNA that directs internal translation initiation.Semantic proximity Read ↗

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