Article
VEGF haplotypes are associated with increased risk to progressive supranuclear palsy and corticobasal syndrome.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Borroni Barbara, Del Bo Roberto, Goldwurm Stefano, Archetti Silvana, Bonvicini Cristian, Agosti Chiara, Bigni Barbara, Papetti Alice, Ghezzi Serena, Sacilotto Giorgio, Pezzoli Gianni, Gennarelli Massimo, Bresolin Nereo, Comi Giacomo Pietro, Padovani Alessandro
Abstract excerpt
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are in the spectrum of tauopathies and recognized to have a strong genetic background. It has been widely reported that MAPT tau haplotype H1 is a genetic risk factor in both conditions, but no other genetic determinants have so far been proposed. Recently, vascular endothelial growth factor (VEGF) haplotypes were reported to confer risk to...
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