Article
Confirmation that Xq27 and Xq28 are susceptibility loci for migraine in independent pedigrees and a case-control cohort.
Neurogenetics - 1 Feb 2012
Maher B H, Kerr M, Cox H C, MacMillan J C, Brimage P J, Esposito T, Gianfrancesco F, Haupt L M, Nyholt D R, Lea R A, Griffiths L R
Abstract excerpt
Investigations into migraine genetics have suggested that susceptibility loci exist on the X chromosome. These reports are supported by evidence that demonstrates male probands as having a higher proportion of affected first-degree relatives as well as the female preponderance of 3:1 that the disorder displays. We have previously implicated the Xq24-28 locus in migraine using two independent multigenerational...
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