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Cyanobacterial Cyclopeptides as Lead Compounds to Novel Targeted Cancer Drugs

15 Mar 2010

Abstract excerpt

Cyanobacterial cyclopeptides, including microcystins and nodularins, are considered a health hazard to humans due to the possible toxic effects of high consumption. From a pharmacological standpoint, microcystins are stable hydrophilic cyclic heptapeptides with a potential to cause cellular damage following uptake via organic anion-transporting polypeptides (OATP). Their intracellular biological effects involve...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20411119
DOI: 10.3390/md8030629

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