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Article

TCRgamma-chain gene rearrangement by GeneScan: incidence and significance of clonal heterogeneity in Sézary syndrome.

The Journal of investigative dermatology - 1 Sept 2010

Fierro Maria T, Ponti Renata, Titli Stefano, Bonello Lisa, Comessatti Alessandra, Novelli Mauro, Fava Paolo, di Celle Paola Francia, Quaglino Pietro, Bernengo Maria Grazia

Abstract excerpt

GeneScan (GS) analysis is a highly sensitive method for the early detection of cutaneous T-cell lymphoma (CTCL) and allows the identification of clonal heterogeneity, defined as the coexistence of two or more different T-cell clones in multiple samples from the same patient. We analyzed by GS the incidence and the significance of long-lived oligoclonal expansions in multiple skin and blood samples from 24 Sézary...

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PMID: 20410915
DOI: 10.1038/jid.2010.97

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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