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Article

The syndromes of reduced sensitivity to thyroid hormone.

Biochimica et biophysica acta - 1 Jul 2013

Dumitrescu Alexandra M, Refetoff Samuel

Abstract excerpt

BACKGROUND: Six known steps are required for the circulating thyroid hormone (TH) to exert its action on target tissues. For three of these steps, human mutations and distinct phenotypes have been identified. SCOPE OF REVIEW: The clinical, laboratory, genetic and molecular characteristics of these three defects of TH action are the subject of this review. The first defect, recognized 45years ago, produces...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22986150
DOI: 10.1016/j.bbagen.2012.08.005
PMCID: PMC3528849

Genes

SECISBP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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