Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inherited defects of thyroid hormone metabolism.

Annales d'endocrinologie - 1 Apr 2011

Dumitrescu A M, Refetoff S

Abstract excerpt

Intracellular metabolism of thyroid hormone and availability of the active hormone, triiodothyronine is regulated by three selenoprotein iodothyronine deiodinases (Ds). While acquired changes in D activities are common, inherited defects in humans have not been identified. Selenium (Se) is an essential trace element required for the biosynthesis of selenoproteins, and selenocysteine insertion sequence (SECIS)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dietary Supplements
Share to Iodide Peroxidase
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RNA-Binding Proteins

Share to Selenium

Share to Selenoproteins

Share to Thyroid Gland

Share to Thyroid Hormones

Source

Open in PubMed Open full text

Identifiers

PMID: 21511232
DOI: 10.1016/j.ando.2011.03.011
PMCID: PMC3094475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inherited defects of thyroid hormone metabolism.PMID 21511232Read ↗

The syndrome of inherited partial SBP2 deficiency in humans.Semantic proximity Read ↗

Inherited Disorders of Thyroid Hormone Metabolism Defect Caused by the Dysregulation of Selenoprotein Expression.Semantic proximity Read ↗

Novel biological and clinical aspects of thyroid hormone metabolism.Semantic proximity Read ↗

Human Genetic Disorders Resulting in Systemic Selenoprotein Deficiency.Semantic proximity Read ↗

Genetic disorders of thyroid development, hormone biosynthesis and signallingSemantic proximity Read ↗

Clinical and molecular characterization of a novel selenocysteine insertion sequence-binding protein 2 (SBP2) gene mutation (R128X).Semantic proximity Read ↗

[Disorders in thyroid hormone metabolism].Semantic proximity Read ↗

Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 DeficiencySemantic proximity Read ↗

A Novel Homozygous Selenocysteine Insertion Sequence Binding Protein 2 (SECISBP2, SBP2) Gene Mutation in a Turkish BoySemantic proximity Read ↗

Clinical and Molecular Analysis in 2 Families With Novel Compound Heterozygous SBP2 (SECISBP2) Mutations.Semantic proximity Read ↗

Human Disorders Affecting the Selenocysteine Incorporation Pathway Cause Systemic Selenoprotein Deficiency.Semantic proximity Read ↗

Selenoprotein-related disease in a young girl caused by nonsense mutations in the SBP2 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.