Article
Inflammatory cytokine gene polymorphisms in gastric cancer cases' and controls' family members from Chinese areas at high cancer prevalence.
Cancer letters - 8 Nov 2008
Feng Yunxia, Zhang Jianzhong, Dai Liping, Zhang Jianying, Wang Peng, Zang Jing, Li Yuchun, Wang Kaijuan
Abstract excerpt
The purpose of this study was to test the associations about Helicobacter pylori infection and polymorphisms of IL-1B-31/-511 and IL-1RN VNTR polymorphism with gastric cancer in cases' and controls' family members from the areas of high cancer prevalence in China. IL-1B-511T and IL-1RN *2 were associated with risks of gastric cancer. The association strength reduced with the relative degree decreasing. Such...
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