Article
Association between Helicobacter pylori infection and interleukin 1 polymorphism predispose to CpG island methylation in gastric cancer
16 Mar 2007
Abstract excerpt
Interleukin1β (IL1β) is upregulated in the presence of Helicobacter pylori infection.1 IL1β polymorphisms with T/T and T/C genotypes enhance IL1β production, and are associated with an increased risk of H pylori -induced hypochlorhydria2 and gastric cancer.3 The relationship between H pylori and CpG island methylation has been repeatedly reported.4–6 It has been reported that IL1β can modulate CpG island...
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