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Article

Dynamics and processes of copy number instability in human gamma-globin genes.

Proceedings of the National Academy of Sciences of the United States of America - 4 May 2010

Neumann Rita, Lawson Victoria E, Jeffreys Alec J

Abstract excerpt

Copy number variation in the human genome is prevalent but relatively little is known about the dynamics of DNA rearrangement. We therefore used the duplicated gamma-globin genes as a simple system to explore de novo copy number changes. Rearrangements that changed gene number were seen in both g...

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Identifiers

PMID: 20404158
DOI: 10.1073/pnas.1003634107
PMCID: PMC2889564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20404158-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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