Pathological consequences of sequence duplications in the human genome.

doi:10.1101/gr.8.10.1007

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Article

Pathological consequences of sequence duplications in the human genome.

Genome research - 1 Oct 1998

Mazzarella R, Schlessinger D

Abstract excerpt

As large-scale sequencing accumulates momentum, an increasing number of instances are being revealed in which genes or other relatively rare sequences are duplicated, either in tandem or at nearby locations. Such duplications are a source of considerable polymorphism in populations, and also incr...

Topics

Gene Duplication
Genetic Predisposition to Disease
Genome, Human
Humans
Repetitive Sequences, Nucleic Acid
X Chromosome

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