Article
Cohesin: an emerging master regulator at the heart of cardiac development.
Molecular biology of the cell - 1 May 2023
Mfarej Michael G, Hyland Caitlin A, Sanchez Annie C, Falk Matthias M, Iovine M Kathryn, Skibbens Robert V
Abstract excerpt
Cohesins are ATPase complexes that play central roles in cellular processes such as chromosome division, DNA repair, and gene expression. Cohesinopathies arise from mutations in cohesin proteins or cohesin complex regulators and encompass a family of related developmental disorders that present with a range of severe birth defects, affect many different physiological systems, and often lead to embryonic fatality....
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