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Article

Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.

Journal of psychosomatic research - 1 May 2010

Holliday Kate L, Macfarlane Gary J, Nicholl Barbara I, Creed Francis, Thomson Wendy, McBeth John

Abstract excerpt

OBJECTIVE: Functional somatic syndromes commonly occur together, share a genetic component and are associated with numerous somatic symptoms. This study aimed to determine if genetic variation in two neuroendocrine systems, the serotoninergic system and the hypothalamic-pituitary-adrenal (HPA) axis, was associated with the number of reported somatic symptoms. METHODS: This population-based cohort study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20403506
DOI: 10.1016/j.jpsychores.2010.01.024
PMCID: PMC2877873

Genes

SERPINA6
TPH2
CRH
CRHBP
CRHR1
POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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