Article
Association of HTR2A polymorphisms with chronic widespread pain and the extent of musculoskeletal pain: results from two population-based cohorts.
Arthritis and rheumatism - 1 Mar 2011
Nicholl Barbara I, Holliday Kate L, Macfarlane Gary J, Thomson Wendy, Davies Kelly A, O'Neill Terence W, Bartfai Gyorgy, Boonen Steven, Casanueva Felipe F, Finn Joseph D, Forti Gianni, Giwercman Aleksander, Huhtaniemi Ilpo T, Kula Krzysztof, Punab Margus, Silman Alan J, Vanderschueren Dirk, Wu Frederick C W, McBeth John
Abstract excerpt
OBJECTIVE: The aim of the current study was to investigate whether genetic variation in genes across the serotoninergic system is associated with chronic widespread pain (CWP) and the number of pain sites reported. METHODS: A discovery cohort, with pain data at 3 time points, was used to investigate genetic associations with 2 phenotypes: 1) CWP (at ≥ 2 time points; n = 164) compared with pain-free controls (at 3...
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