Article
Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial.
The American journal of cardiology - 1 May 2010
Shiffman Dov, Sabatine Marc S, Louie Judy Z, Kirchgessner Todd G, Iakoubova Olga A, Campos Hannia, Devlin James J, Sacks Frank M
Abstract excerpt
A previous genetic analysis of the Cholesterol and Recurrent Events (CARE) trial found that carriers of the 719Arg allele of the kinesin family member 6 gene (KIF6) (rs20455), but not noncarriers, received significant event reduction from pravastatin therapy. However, that previous analysis of CA...
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