<i>KIF6</i> Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study

Abstract excerpt

BACKGROUND: Statin therapy has been found to substantially and significantly reduce coronary events in carriers of the KIF6 719Arg variant (rs20455) but not in noncarriers. We investigated whether, among the elderly, statin therapy also significantly reduced coronary events in carriers but not in noncarriers. DESIGN AND METHODS: Among 5,752 patients of the PROspective Study of Pravastatin in the Elderly at Risk...

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