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Article

The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B.

Journal of leukocyte biology - 1 Jul 2010

Rosas Marcela, Thomas Benjamin, Stacey Martin, Gordon Siamon, Taylor Philip R

Abstract excerpt

This study aimed to identify the inflammation-associated 7/4-antigen, which is highly expressed on neutrophils, inflammatory monocytes, some activated macrophages, as well as on bone marrow myeloid-restricted progenitors. The high expression on inflammatory cells is suggestive of a role in inflammation and makes the 7/4-antigen a potential target for the manipulation of inflammatory cells. Consistent with this,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20400676
DOI: 10.1189/jlb.0809548
PMCID: PMC2892525

Genes

CCR2
CIITA
GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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