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Article

Alpha-synuclein nitration and autophagy response are induced in peripheral blood cells from patients with Parkinson disease.

Neuroscience letters - 14 Jun 2010

Prigione Alessandro, Piazza Fabrizio, Brighina Laura, Begni Barbara, Galbussera Alessio, Difrancesco Jacopo C, Andreoni Simona, Piolti Roberto, Ferrarese Carlo

Abstract excerpt

Several lines of evidence implicate a central role for alpha-synuclein (aSN) in the pathogenesis of Parkinson's disease (PD). Besides rare genetic mutations, post-translational mechanisms, such as oxidative stress-related nitration, may alter the protein properties in terms of propensity to aggregate or be degraded. Our group previously described increased reactive oxygen species (ROS) production within easily...

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PMID: 20399833
DOI: 10.1016/j.neulet.2010.04.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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