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Article

Improvement of a quantitative cell tropism assay for rapid and reliable characterization of human cytomegalovirus mutants.

Journal of virological methods - 1 Aug 2010

Schuessler Andrea, Sampaio Kerstin Laib, Sinzger Christian

Abstract excerpt

Endothelial cell tropism is an inherent property of isolates of human cytomegalovirus (HCMV), and has been proposed as a pathogenicity factor of HCMV. Mutational approaches can be applied for analysis of the molecular determinants of endothelial cell tropism, but the evaluation of mutants is limited by the low reliability of the widely employed cell tropism assay. The aim of this study was to improve the assay...

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Identifiers

PMID: 20399230
DOI: 10.1016/j.jviromet.2010.03.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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