Human Cytomegalovirus Tropism for Endothelial Cells: Not All Endothelial Cells Are Created Equal

Abstract excerpt

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that persists for the life of the host following initial infection.Genome analysis indicates that mammalian CMVs have cospeciated with their respective host over the last 80 million years (39).This prolonged period of coevolution has resulted in a high level of coadaptation between virus and host.The study of CMV, a virus that is exquisitely adapted for...

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