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Article

The quest for molecular quasi-species in ligand-activity space and its application to directed enzyme evolution.

FEBS letters - 18 Jun 2010

Mannervik Bengt, Runarsdottir Arna

Abstract excerpt

We propose that the proper evolving unit in enzyme evolution is not a single "fittest molecule", but a cluster of related variants denoted a "quasi-species". A distribution of variants provides genetic variability and thereby reduces the risk of inbreeding and evolutionary dead-ends. Different ma...

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Identifiers

PMID: 20399208
DOI: 10.1016/j.febslet.2010.04.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20399208-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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