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Article

Multivariate-activity mining for molecular quasi-species in a glutathione transferase mutant library.

Protein engineering, design & selection : PEDS - 1 May 2007

Kurtovic Sanela, Runarsdottir Arna, Emrén Lars O, Larsson Anna-Karin, Mannervik Bengt

Abstract excerpt

A library of recombinant glutathione transferases (GSTs) generated by shuffling of DNA encoding human GST M1-1 and GST M2-2 was screened with eight alternative substrates, and the activities were subjected to multivariate analysis. Assays were made in lysates of bacteria in which the GST variants had been expressed. The primary data showed clustering of the activities in eight-dimensional substrate-activity...

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PMID: 17468114
DOI: 10.1093/protein/gzm017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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