Article
Exploring Inflammatory Asthma Phenotypes: Proteomic Signatures in Serum and Induced Sputum.
International journal of molecular sciences - 20 Mar 2024
Maia Larissa Prado, Cunha Thulio Marquez, Santos Paula Souza, Martins Mario Machado, Briza Peter, Ferreira Fatima, Amorim Maria Marta, Caetano Lilian Ballini, Farias Camyla Fernandes, Santoro Ilka Lopes, Godoy Fernandes Ana Luisa, Goulart Luiz Ricardo
Abstract excerpt
Asthma drug responses may differ due to inflammatory mechanisms triggered by the immune cells in the pulmonary microenvironment. Thus, asthma phenotyping based on the local inflammatory profile may aid in treatment definition and the identification of new therapeutic targets. Here, we investigated protein profiles of induced sputum and serum from asthma patients classified into eosinophilic, neutrophilic, mixed...
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