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Article

Rare corneal clones in mice suggest an age-related decrease of stem cell activity and support the limbal epithelial stem cell hypothesis.

Stem cell research - 1 Jan 2012

Douvaras Panagiotis, Webb Sheila, Whitaker Duncan A, Dorà Natalie, Hill Robert E, Dorin Julia R, West John D

Abstract excerpt

The anterior ocular surface comprises the cornea, conjunctiva and a narrow intermediate region called the limbus. It is widely accepted that the corneal epithelium is maintained by stem cells but different hypotheses propose that the stem cells that maintain the mouse corneal epithelium during normal homeostasis are located either in the basal limbal epithelium or throughout the basal corneal epithelium. There...

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PMID: 22099025
DOI: 10.1016/j.scr.2011.08.007

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KRT5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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