Article
DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 14 Apr 2010
Schulte Joost, Sepp Katharine J, Jorquera Ramon A, Wu Chaohong, Song Yun, Hong Pengyu, Littleton J Troy
Abstract excerpt
The monopolar spindle-one-binder (Mob) family of kinase-interacting proteins regulate cell cycle and cell morphology, and their dysfunction has been linked to cancer. Models for Mob function are primarily based on studies of Mob1 and Mob2 family members in yeast. In contrast, the function of the highly conserved metazoan Phocein/Mob3 subfamily is unknown. We identified the Drosophila Phocein homolog (DMob4) as a...
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