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Article

Immunohistochemical expression of BRCA1 and lethal prostate cancer.

Cancer research - 15 Apr 2010

Fiorentino Michelangelo, Judson Gregory, Penney Kathryn, Flavin Richard, Stark Jennifer, Fiore Christopher, Fall Katja, Martin Neil, Ma Jing, Sinnott Jennifer, Giovannucci Edward, Stampfer Meir, Sesso Howard D, Kantoff Philip W, Finn Stephen, Loda Massimo, Mucci Lorelei

Abstract excerpt

BRCA1 functions as a tumor suppressor; recent work suggests that BRCA1 may also induce cell cycle arrest to allow for DNA repair. We hypothesized that BRCA1 expression in prostate tumor tissue may be associated with prostate cancer progression through regulation of the cell cycle. We used immunoh...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genes, BRCA1

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Share to Oligonucleotide Array Sequence Analysis

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Source

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Identifiers

PMID: 20388772
DOI: 10.1158/0008-5472.CAN-09-4100
PMCID: PMC3049266

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20388772-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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