Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of RAD51 occurs in aggressive prostatic cancer.

Histopathology - 1 Dec 2009

Mitra Anita, Jameson Charles, Barbachano Yolanda, Sanchez Lydia, Kote-Jarai Zsofia, Peock Susan, Sodha Nayanta, Bancroft Elizabeth, Fletcher Anne, Cooper Colin, Easton Douglas, Eeles Rosalind, Foster Christopher S

Abstract excerpt

AIMS: To test the hypothesis that, in a matched series of prostatic cancers, either with or without BRCA1 or BRCA2 mutations, RAD51 protein expression is enhanced in association with BRCA mutation genotypes. METHODS AND RESULTS: RAD51 expression identified immunohistochemically was compared between prostatic cancers occurring in BRCA1 or BRCA2 mutation carriers and controls. RAD51 protein expression in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Count

Share to Germ-Line Mutation

Share to Neoplasm Proteins

Share to Prostatic Neoplasms

Share to Rad51 Recombinase

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 20002770
DOI: 10.1111/j.1365-2559.2009.03448.x
PMCID: PMC2856636

Genes

RAD51
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Overexpression of RAD51 occurs in aggressive prostatic cancer.PMID 20002770Read ↗

Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response proteinSemantic proximity Read ↗

RAD51 as a potential surrogate marker for DNA repair capacity in solid malignanciesSemantic proximity Read ↗

HP1γ expression is elevated in prostate cancer and is superior to Gleason score as a predictor of biochemical recurrence after radical prostatectomySemantic proximity Read ↗

Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesisSemantic proximity Read ↗

Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad51 as a tumour-associated antigenSemantic proximity Read ↗

High RAD51 mRNA expression characterize estrogen receptor‐positive/progesteron receptor‐negative breast cancer and is associated with patient's outcomeSemantic proximity Read ↗

Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancerSemantic proximity Read ↗

DKC1 overexpression associated with prostate cancer progressionSemantic proximity Read ↗

Epigenetic events, remodelling enzymes and their relationship to chromatin organization in prostatic intraepithelial neoplasia and prostatic adenocarcinoma.Semantic proximity Read ↗

Characterisation of the promoter region of the human DNA-repair gene Rad51.Semantic proximity Read ↗

Immunohistochemical expression of BRCA1 and lethal prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.