Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Individual carboxypeptidase D domains have both redundant and unique functions in Drosophila development and behavior.

Cellular and molecular life sciences : CMLS - 1 Sept 2010

Sidyelyeva Galyna, Wegener Christian, Schoenfeld Brian P, Bell Aaron J, Baker Nicholas E, McBride Sean M J, Fricker Lloyd D

Abstract excerpt

Metallocarboxypeptidase D (CPD) functions in protein and peptide processing. The Drosophila CPD svr gene undergoes alternative splicing, producing forms containing 1-3 active or inactive CP domains. To investigate the function of the various CP domains, we created transgenic flies expressing specific forms of CPD in the embryonic-lethal svr (PG33) mutant. All constructs containing an active CP domain rescued the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Animals, Genetically Modified

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Gene Components

Share to Memory

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Wings, Animal

Source

Open in PubMed Open full text

Identifiers

PMID: 20386952
DOI: 10.1007/s00018-010-0369-8
PMCID: PMC2922403

Genes

CP
CPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Individual carboxypeptidase D domains have both redundant and unique functions in Drosophila development and behavior.PMID 20386952Read ↗

Characterization of the molecular basis of the Drosophila mutations in carboxypeptidase D. Effect on enzyme activity and expression.Semantic proximity Read ↗

Characterization of Drosophila carboxypeptidase D.Semantic proximity Read ↗

The DCBLD receptor family: emerging signaling roles in development, homeostasis and diseaseSemantic proximity Read ↗

Expression and characterization of Drosophila signal peptide peptidase-like (sppL), a gene that encodes an intramembrane protease.Semantic proximity Read ↗

Cloning of the neurodegeneration gene drop-dead and characterization of additional phenotypes of its mutation.Semantic proximity Read ↗

Divergent functions through alternative splicing: the Drosophila CRMP gene in pyrimidine metabolism, brain, and behavior.Semantic proximity Read ↗

Drosophila KDEL receptor function in the embryonic salivary gland and epidermis.Semantic proximity Read ↗

Transcriptional changes revealed genes and pathways involved in the deficient testis caused by the inhibition of alkaline ceramidase (Dacer) in Drosophila melanogaster.Semantic proximity Read ↗

Differential expansion and evolution of the exon family encoding the Serpin-1 reactive centre loop has resulted in divergent serpin repertoires among the Lepidoptera.Semantic proximity Read ↗

Drosophila signal peptidase complex member Spase12 is required for development and cell differentiation.Semantic proximity Read ↗

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defectsSemantic proximity Read ↗

The Caenorhabditis elegans ERp60 Homolog Protein Disulfide Isomerase-3 Has Disulfide Isomerase and Transglutaminase-like Cross-linking Activity and Is Involved in the Maintenance of Body MorphologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.