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Article

Novel FUS/TLS mutations and pathology in familial and sporadic amyotrophic lateral sclerosis.

Archives of neurology - 1 Apr 2010

Hewitt Christopher, Kirby Janine, Highley J Robin, Hartley Judith A, Hibberd Rachael, Hollinger Hannah C, Williams Tim L, Ince Paul G, McDermott Christopher J, Shaw Pamela J

Abstract excerpt

OBJECTIVE: To determine the frequency of and clinicopathologic phenotypes associated with FUS/TLS mutations in a large cohort of amyotrophic lateral sclerosis (ALS) cases from the north of England. DESIGN: Genetic screening project with neuropathologic examination of postmortem tissue in selected cases. The clinical details of selected cases are also presented. SETTING: Neurology departments of 2 university...

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Source

Identifiers

PMID: 20385912
DOI: 10.1001/archneurol.2010.52

Genes

FUS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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