Article
Identification of novel FUS mutations in sporadic cases of amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases - 1 Mar 2011
Belzil Veronique V, Daoud Hussein, St-Onge Judith, Desjarlais Anne, Bouchard Jean-Pierre, Dupre Nicolas, Lacomblez Lucette, Salachas François, Pradat Pierre-François, Meininger Vincent, Camu William, Dion Patrick A, Rouleau Guy A
Abstract excerpt
Mutations in the FUS gene have been recently associated with amyotrophic lateral sclerosis (ALS). While most of the variants have been identified in patients with a family history of the disease, a few mutations were also found in sporadic patients. Considering this, we wanted to evaluate the frequency of mutations in the coding region of the FUS gene in a sporadic ALS (SALS) cohort compared to a control...
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