Article
Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Su C, Picard P, Rathbone M P, Jiang S
Abstract excerpt
Cancers contain a 'side population' (SP), a subset of cells that is greatly enriched in stem cells and which contains malignant progenitors. SP cells are characterised by high efflux capability for Hoechst 33342 dye and for anti-cancer therapeutic agents through transporters; ABCG2 (ATP-binding cassette transporter G2) is currently most closely associated with the SP phenotype. Guanosine is an important...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
