Pathogenesis of type 2 diabetes mellitus.

doi:10.1055/s-2001-18577

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Article

Pathogenesis of type 2 diabetes mellitus.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 2001

Dostou J, Gerich J

Abstract excerpt

Type 2 diabetes mellitus is a heterogeneous disorder with genetic and acquired components. It is primarily due to impaired insulin secretion in that individuals with genetically impaired beta cell function cannot increase their insulin release sufficiently to compensate for insulin resistance. The resultant hyperglycemia is largely the consequence of excessive release of endogenous glucose due to increased...

Topics

Diabetes Mellitus, Type 2
Genetic Predisposition to Disease
Humans
Hyperglycemia
Insulin
Insulin Resistance
Insulin Secretion
Postprandial Period

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Open in PubMed

Identifiers

PMID: 11460566
DOI: 10.1055/s-2001-18577

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