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Article

Conserved determinants of enhanced CCR5 binding in the human immunodeficiency virus subtype D envelope third variable loop.

AIDS research and human retroviruses - 1 Apr 2010

Teeravechyan Samaporn, Essex M, Lee Tun-Hou

Abstract excerpt

Human immunodeficiency virus 1 subtype D (HIV-1D) contributes to a significant portion of the HIV-1 disease burden in eastern and central Africa, and is associated with more rapid disease progression. Its viral envelope sequences, particularly in the third variable region (V3), are highly divergent from other major subtypes yet have rarely been studied to date. We evaluated the V3 and select bridging sheet...

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Topics

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Share to Conserved Sequence
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to Mutagenesis, Site-Directed

Share to Peptide Fragments

Share to Receptors, CCR5

Share to Virus Attachment

Share to Virus Internalization

Source

Open in PubMed Open full text

Identifiers

PMID: 20377425
DOI: 10.1089/aid.2009.0086
PMCID: PMC2864059

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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