Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Net positive charge of HIV-1 CRF01_AE V3 sequence regulates viral sensitivity to humoral immunity.

PloS one - 12 Sept 2008

Naganawa Satoshi, Yokoyama Masaru, Shiino Teiichiro, Suzuki Takeyuki, Ishigatsubo Yoshiaki, Ueda Atsuhisa, Shirai Akira, Takeno Mitsuhiro, Hayakawa Satoshi, Sato Shigehiro, Tochikubo Osamu, Kiyoura Shingo, Sawada Kaori, Ikegami Takashi, Kanda Tadahito, Kitamura Katsuhiko, Sato Hironori

Abstract excerpt

The third variable region (V3) of the human immunodeficiency virus type 1 (HIV-1) envelope gp120 subunit participates in determination of viral infection coreceptor tropism and host humoral immune responses. Positive charge of the V3 plays a key role in determining viral coreceptor tropism. Here,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Formation
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to Immune System

Share to Models, Statistical

Share to Molecular Conformation

Share to Neutralization Tests

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 18787705
DOI: 10.1371/journal.pone.0003206
PMCID: PMC2527523

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18787705-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Net positive charge of HIV-1 CRF01_AE V3 sequence regulates viral sensitivity to humoral immunity.PMID 18787705Read ↗

Structural dynamics of HIV-1 envelope Gp120 outer domain with V3 loop.Semantic proximity Read ↗

Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization SensitivitySemantic proximity Read ↗

Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies.Semantic proximity Read ↗

Appreciating HIV type 1 diversity: subtype differences in Env.Semantic proximity Read ↗

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule.Semantic proximity Read ↗

Protein Structural Disorder Of The Envelope V3 Loop Contributes To The Switch In Human Immunodeficiency Virus Type 1 Cell TropismSemantic proximity Read ↗

Alternative substitutions of N332 in HIV-1 AD8 gp120 differentially affect envelope glycoprotein function and viral sensitivity to broadly neutralizing antibodies targeting the V3-glycanSemantic proximity Read ↗

Hypervariable region 3 residues of HIV type 1 gp120 involved in CCR5 coreceptor utilization: therapeutic and prophylactic implications.Semantic proximity Read ↗

Identification and structural characterization of novel genetic elements in the HIV-1 V3 loop regulating coreceptor usage.Semantic proximity Read ↗

Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop.Semantic proximity Read ↗

Predicting HIV-1 coreceptor usage with sequence analysis.Semantic proximity Read ↗

HIV-1 gp120 V3 Loop for Structure-Based Drug DesignSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.