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TSLC1 gene silencing in cutaneous melanoma

7 Apr 2010

Abstract excerpt

Tumor suppressor in lung cancer 1 (TSLC1) is a tumor suppressor gene that encodes a member of the immunoglobulin superfamily, which is involved in the progression of some types of cancer. Several studies have shown that loss of TSLC1 expression is strongly correlated to methylation of the gene promoter, thus leading to poor prognosis in these cancers. However, the role of TSLC1 in cutaneous melanoma (CM) has not...

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PMID: 20375924
DOI: 10.1097/cmr.0b013e32833413c0

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