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Article

Promoter methylation of the TSLC1 gene in advanced lung tumors and various cancer cell lines.

International journal of cancer - 20 Oct 2003

Fukami Takeshi, Fukuhara Hiroshi, Kuramochi Masami, Maruyama Tomoko, Isogai Kana, Sakamoto Michiie, Takamoto Shinichi, Murakami Yoshinori

Abstract excerpt

We previously identified TSLC1, a tumor suppressor gene in human nonsmall cell lung cancer (NSCLC). TSLC1 belongs to immunoglobulin superfamily molecules and is involved in cell adhesion. Loss of TSLC1 expression was strongly correlated with the promoter hypermethylation in several NSCLC cell lines. Here, we examined the methylation status of the TSLC1 gene promoter in 48 primary NSCLC tumors by bisulfite SSCP in...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Loss of Heterozygosity

Share to Polymorphism, Single-Stranded Conformational

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Identifiers

PMID: 12925956
DOI: 10.1002/ijc.11348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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