Microarray-Based Detection of <i>CYP1A1</i> , <i>CYP2C9</i> , <i>CYP2C19</i> , <i>CYP2D6</i> , <i>GSTT1</i> , <i>GSTM1</i> , <i>MTHFR</i> , <i>MTRR</i> , <i>NQO1</i> , <i>NAT2</i> , <i>HLA-DQA1</i> , and <i>AB0</i> Allele Frequencies in Native Russians

Abstract excerpt

Xenobiotic-metabolizing genes (e.g., Cytochromes P450, GST, NAT2, and NQO1), folate metabolism genes (e.g., MTHFR and MTRR), and major histocompatibility complex genes (e.g., HLA-DQA1) play multiple roles in the organism functioning. In addition, AB0 is the most clinically significant high-polymorphic gene in transfusion and transplantation medicine. Epidemiological data show that allele frequencies of these...

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