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Article

Ethnic differences in cytokine gene polymorphisms: potential implications for cancer development.

Cancer immunology, immunotherapy : CII - 1 Jan 2008

Zabaleta Jovanny, Schneider Barbara G, Ryckman Kelli, Hooper Pleasant F, Camargo M Constanza, Piazuelo M Blanca, Sierra Rosa A, Fontham Elizabeth T H, Correa Pelayo, Williams Scott M, Ochoa Augusto C

Abstract excerpt

Differences in incidence and outcome of cancer among ethnic groups may be explained by biological and/or socio-economic factors. Genetic variations that affect chronic inflammation, a potentially important risk factor for carcinogenesis, may differ across ethnic groups. Such differences may help explain cancer disparities among these groups. Single nucleotide polymorphisms (SNPs) within cytokine genes can affect...

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Identifiers

PMID: 17618436
DOI: 10.1007/s00262-007-0358-4
PMCID: PMC11031046

Genes

TNF

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