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Article

The ATDC (TRIM29) Protein Binds p53 and Antagonizes p53-Mediated Functions

5 Apr 2010

Abstract excerpt

The ataxia telangiectasia group D-complementing (ATDC) gene product, also known as TRIM29, is a member of the tripartite motif (TRIM) protein family. ATDC has been proposed to form homo- or heterodimers and to bind nucleic acids. In cell cultures, ATDC expression leads to rapid growth and resistance to ionizing radiation (IR), whereas silencing of ATDC expression decreases growth rates and increases sensitivity...

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PMID: 20368352
DOI: 10.1128/mcb.01023-09

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