Article
Mutations in N-cadherin and a Stardust homolog, Nagie oko, affect cell-cycle exit in zebrafish retina.
Mechanisms of development - 1 Jan 2000
Yamaguchi Masahiro, Imai Fumiyasu, Tonou-Fujimori Noriko, Masai Ichiro
Abstract excerpt
It has been reported that the loss of apicobasal cell polarity and the disruption of adherens junctions induce hyperplasia in the mouse developing brain. However, it is not fully understood whether hyperplasia is caused by an enhanced cell proliferation, an inhibited neurogenesis, or both. In this study, we found that the ratio of the number of proliferating progenitor cells to the total number of retinal cells...
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