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Article

Expanded progenitor populations, vitreo-retinal abnormalities, and Müller glial reactivity in the zebrafish leprechaun/patched2 retina.

BMC developmental biology - 19 Oct 2009

Bibliowicz Jonathan, Gross Jeffrey M

Abstract excerpt

BACKGROUND: The roles of the Hedgehog (Hh) pathway in controlling vertebrate retinal development have been studied extensively; however, species- and context-dependent findings have provided differing conclusions. Hh signaling has been shown to control both population size and cell cycle kinetics of proliferating retinal progenitors, and to modulate differentiation within the retina by regulating the timing of...

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PMID: 19840373
DOI: 10.1186/1471-213X-9-52
PMCID: PMC2770046

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