Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Robust activation of the human but not mouse telomerase gene during the induction of pluripotency

30 Mar 2010

Abstract excerpt

Pluripotent stem cells (PSCs) express telomerase and have unlimited proliferative potential. To study telomerase activation during reprogramming, 3 classes of embryonic stem cell (ESC)-like clones were isolated from mouse fibroblasts containing a transgenic hTERT reporter. Class I expressed few pluripotency markers, whereas class II contained many, but not Oct4, Nanog, and Sox2. Neither class of cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20354136
DOI: 10.1096/fj.09-148973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Robust activation of the human but not mouse telomerase gene during the induction of pluripotencyPMID 20354136Read ↗

Telomerase dynamics in stem cells: Unraveling the molecular nexus of cellular aging and regenerationSemantic proximity Read ↗

Telomerase-mediated telomere elongation from human blastocysts to embryonic stem cellsSemantic proximity Read ↗

A Key Role for Telomerase Reverse Transcriptase Unit in Modulating Human Embryonic Stem Cell Proliferation, Cell Cycle Dynamics, and In Vitro DifferentiationSemantic proximity Read ↗

Human Specific Regulation of the Telomerase Reverse Transcriptase GeneSemantic proximity Read ↗

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomeraseSemantic proximity Read ↗

Taking the brakes off telomerase.Semantic proximity Read ↗

mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cellsSemantic proximity Read ↗

Telomere dynamics in human pluripotent stem cellsSemantic proximity Read ↗

Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.Semantic proximity Read ↗

Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cellsSemantic proximity Read ↗

Generation and Characterization of an Immortalized Human Mesenchymal Stromal Cell LineSemantic proximity Read ↗

Short Telomeres in ESCs Lead to Unstable DifferentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.