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Article

Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort.

Arthritis research & therapy - 1 Jan 2010

Morgan Ann W, Robinson James I, Conaghan Philip G, Martin Stephen G, Hensor Elizabeth M A, Morgan Michael D, Steiner Lori, Erlich Henry A, Gooi Hock-Chye, Barton Anne, Worthington Jane, Emery Paul

Abstract excerpt

INTRODUCTION: This study investigated five confirmed rheumatoid arthritis (RA) susceptibility genes/loci (HLA-DRB1, PTPN22, STAT4, OLIG3/TNFAIP3 and TRAF1/C5) for association with susceptibility and severity in an inception cohort. METHODS: The magnitude of association for each genotype was assessed in 1,046 RA subjects from the Yorkshire Early RA cohort and in 5,968 healthy UK controls. Additional exploratory...

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Source

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Identifiers

PMID: 20353580
DOI: 10.1186/ar2969
PMCID: PMC2888207

Genes

TRAF1
PTPN22
OLIG3
TNFAIP3
STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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