Article
Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls.
Arthritis research & therapy - 1 Jan 2009
Stark Klaus, Rovenský Jozef, Blazicková Stanislava, Grosse-Wilde Hans, Ferencik Stanislav, Hengstenberg Christian, Straub Rainer H
Abstract excerpt
INTRODUCTION: Both genetic and environmental factors contribute to rheumatoid arthritis (RA), a common and complex autoimmune disease. As well as the major susceptibility gene HLA-DRB1, recent genome-wide and candidate-gene studies reported additional evidence for association of single nucleotide polymorphism (SNP) markers in the PTPN22, STAT4, OLIG3/TNFAIP3 and TRAF1/C5 loci with RA. This study was initiated to...
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