Article
A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA.
Arthritis and rheumatism - 15 Dec 2009
Kolfenbach Jason R, Deane Kevin D, Derber Lezlie A, O'Donnell Colin, Weisman Michael H, Buckner Jane H, Gersuk Vivian H, Wei Shan, Mikuls Ted R, O'Dell James, Gregersen Peter K, Keating Richard M, Norris Jill M, Holers V Michael
Abstract excerpt
OBJECTIVE: To describe a large, multicenter prospective cohort study of first-degree relatives (FDRs) of probands with rheumatoid arthritis (RA), and outline the use of such a study in investigating the natural history of RA development. METHODS: A total of 1,058 FDRs, none of whom met the American College of Rheumatology criteria for RA, were enrolled in a prospective study investigating genetic and...
Topics
Join the communities discussing this publication.