Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery.

doi:10.1634/theoncologist.2009-0233

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Article

Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery.

The oncologist - 1 Jan 2010

Tejpar Sabine, Bertagnolli Monica, Bosman Fred, Lenz Heinz-Joseph, Garraway Levi, Waldman Frederic, Warren Robert, Bild Andrea, Collins-Brennan Denise, Hahn Hejin, Harkin D Paul, Kennedy Richard, Ilyas Mohammad, Morreau Hans, Proutski Vitali, Swanton Charles, Tomlinson Ian, Delorenzi Mauro, Fiocca Roberto, Van Cutsem Eric, Roth Arnaud

Abstract excerpt

The number of agents that are potentially effective in the adjuvant treatment of locally advanced resectable colon cancer is increasing. Consequently, it is important to ascertain which subgroups of patients will benefit from a specific treatment. Despite more than two decades of research into the molecular genetics of colon cancer, there is a lack of prognostic and predictive molecular biomarkers with proven...

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PMID: 20350999
DOI: 10.1634/theoncologist.2009-0233
PMCID: PMC3227961

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