Article
Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers.
British journal of cancer - 17 Sept 2007
Detours V, Delys L, Libert F, Weiss Solís D, Bogdanova T, Dumont J E, Franc B, Thomas G, Maenhaut C
Abstract excerpt
Papillary thyroid cancers (PTCs) incidence dramatically increased in the vicinity of Chernobyl. The cancer-initiating role of radiation elsewhere is debated. Therefore, we searched for a signature distinguishing radio-induced from sporadic cancers. Using microarrays, we compared the expression profiles of PTCs from the Chernobyl Tissue Bank (CTB, n=12) and from French patients with no history of exposure to...
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